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Mesterolone is a synthetic anabolic-androgenic steroid (AAS) and derivative of dihydrotestosterone (DHT). It is inactivated by 3α-hydroxysteroid dehydrogenase in skeleta muscules so it is considered a weak androgen. It is not a substrate for aromatase so it is not converted into estrogen. Mesterolone demonstrated to have minimal effect on sperm counts and levels of FSH or LH. Experiments of mesterolone serving as a potential treatment of depression are still undergoing.
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Unlike many other steroids, this one is taken orally and is commonly used to treat deficiency of male sex hormones. We’ll go into the uses for Mesterolone below. Before that though, let’s take a quick look at how it works.
The belief that the weak anabolic nature of this compound indicates a tendency to block the androgen receptor in muscle tissue, thereby reducing the gains of other more potent muscle-building steroids, should likewise not be taken seriously. In fact, due to its extremely high affinity for plasma binding proteins such as SHBG, mesterolone may actually work to potentate the activity of other steroids by displacing a higher percentage into a free, unbound state. Among athletes, mesterolone is primarily used to increase androgen levels when dieting or preparing for a contest, and as an anti-estrogen due to its intrinsic ability to antagonize the aromatase enzyme.
Dosage can vary between 50 to 150 mg depending on need and goals. Since it is more androgenic rather than anabolic, this steroid works by increasing androgen receptors in the body. What this means is that it won’t actively increase or affect production or testosterone levels but it will help with male sex traits and to a large extent reduce the production in estrogen which often causes the main side effects of many steroids.
Some negative side effects of Generic Proviron 25mg include:
- Suppression of testosterone
- Increased levels of bad cholesterol – this means increased risk of heart problems
- Excessive growth of hair
- Issues with high blood pressure