Buy Sirolimus. Generic Rapamune Online

Sirolimus has immunosuppressant functions in humans and is especially useful in preventing the rejection of kidney transplants.


Active substance Sirolimus
US Brand Rapamune 
IN Brand Rapacan 1
Made by Biocon
Strength 1mg
Form release blister 10 tablets
Shipping time 7 – 18 days
Order
through request form


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Sirolimus is used with other medications to prevent rejection of a kidney transplant.

Sirolimus available for buying in India under brand name Rapacan, you can order Generic Rapamune with delivery to USA, UK, AU, through request page.

Sirolimus is used together with other medicines to prevent the body from rejecting a transplanted kidney. It belongs to a group of medicines known as immunosuppressive agents.

When a patient receives an organ transplant, the body’s white blood cells will try to get rid of (reject) the transplanted organ. Sirolimus works by preventing the white blood cells from getting rid of the transplanted organ.

Sirolimus is a very strong medicine. It can cause side effects that can be very serious, such as kidney problems. It may also reduce the body’s ability to fight infections. You and your doctor should talk about the benefits of this medicine as well as the risks.

Sirolimus is also used to treat lymphangioleiomyomatosis, a rare lung disease that affects predominantly women of childbearing age.

The dose of this medicine will be different for different patients. Follow your doctor’s orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For oral dosage forms (oral solution or tablets):
    • For prevention of kidney transplant rejection:
      • Adults and children 13 years of age and older weighing 40 kilograms (kg) or more—2 milligrams (mg) per day after an initial one-time dose of 6 mg. Some patients may require a dose of up to 5 mg per day after an initial one-time dose of 15 mg. However, the dose is usually not more than 40 mg per day.
      • Children 13 years of age and older weighing less than 40 kg—Dose is based on body size as determined by your doctor. The dose is 1 milligram (mg) per square meter [m(2)] of body surface area once a day after an initial one-time dose of 3 mg per square meter [m(2)] of body surface area.
      • Children younger than 13 years of age—Use and dose must be determined by your doctor.
    • For treatment of lymphangioleiomyomatosis:
      • Adults—At first, 2 milligrams (mg) per day. Your doctor may adjust your dose as needed.
      • Children—Use and dose must be determined by your doctor.

Storage

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store the tablets at room temperature in a closed container, away from heat, moisture, and direct light.

Store the oral liquid in the refrigerator. Protect it from direct light and moisture. Do not freeze. You may store the oral liquid at room temperature for a short period of time (not more than 15 days). If you see a slight haze or cloudiness in the bottle, leave it out at room temperature and shake it until the haze disappears. Throw away any unused medicine after 30 days.

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common
  1. Abdominal or stomach cramps or pain
  2. accumulation of pus
  3. anxiousness, unexplained
  4. backache
  5. black or red, tarry stools
  6. bleeding from the gums or nose
  7. blurred vision
  8. body aches or pain
  9. bone pain
  10. bruising
  11. burning or stinging of the skin
  12. burning while urinating
  13. burning, dry, or itching eyes
  14. burning, tingling, numbness, or pain in the hands, arms, feet, or legs
  15. change in mental status
  16. changes in skin color
  17. chest pain
  18. chills
  19. confusion
  20. convulsions (seizures)
  21. cough
  22. dark or bloody urine
  23. deafness
  24. decreased urine output
  25. decreased vision
  26. difficulty with breathing or swallowing
  27. dilated neck veins
  28. discharge from the eyes
  29. dizziness
  30. drowsiness
  31. dry mouth
  32. earache
  33. excessive tearing
  34. extreme fatigue
  35. eye pain
  36. facial hair growth in females
  37. faintness or lightheadedness when getting up from lying or sitting position
  38. fast, slow, or irregular heartbeat
  39. fever
  40. flushing or redness of the skin, especially on the face and neck
  41. general feeling of discomfort or illness
  42. increased hunger
  43. increased menstrual flow or vaginal bleeding
  44. itching, pain, redness, swelling, tenderness, or warmth on the skin
  45. lack or loss of appetite
  46. large, flat, blue, or purplish patches in the skin
  47. loss of sexual ability, desire, drive, or performance
  48. loss of voice
  49. muscle pain
  50. nasal congestion
  51. nausea or vomiting
  52. numbness or tingling around the lips, hands, or feet
  53. pain in the chest, groin, or legs, especially the calves
  54. painful cold sores or blisters on the lips, nose, eyes, or genitals
  55. pale skin
  56. prolonged bleeding from cuts
  57. rapid heartbeat
  58. rash
  59. red or dark brown urine
  60. redness or swelling in the ear
  61. redness, pain, or swelling of the eye, eyelid, or inner lining of the eyelid
  62. ringing in the ears
  63. runny nose
  64. sensation of pins and needles
  65. severe constipation
  66. severe vomiting
  67. severe, sudden headache
  68. slurred speech
  69. sore throat
  70. sores or white spots on the lips or in the mouth
  71. stomach pain or upset
  72. sudden decrease in the amount of urine
  73. sudden loss of coordination
  74. sudden, severe weakness or numbness in the arm or leg
  75. sudden, unexplained shortness of breath
  76. sweating
  77. swollen, painful, or tender lymph glands in the neck, armpit, or groin
  78. tenderness, pain, swelling, warmth, skin discoloration, and prominent superficial veins over affected area
  79. tremor
  80. ulcers on the lips or in the mouth
  81. unusual tiredness or weakness
  82. vision changes
  83. weakness or heaviness of the legs
  84. white patches in the mouth or on the tongue
  85. yellow skin and eyes
Less common
  1. Bloating
  2. change in size, shape, or color of existing mole
  3. hoarseness
  4. mole that leaks fluid or bleeds
  5. new mole
  6. pains in the stomach, side or abdomen, possibly radiating to the back
  7. skin ulcer or sores
Incidence not known
  1. Abnormal wound healing
  2. headache
  3. hives or itching
  4. large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  5. nails loose or detached
  6. puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  7. swelling of the arms or legs
  8. yellow nails lacking a cuticle

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common
  1. Abnormal vision
  2. acne
  3. belching
  4. blistering, crusting, irritation, itching, or reddening of the skin
  5. burning feeling in the chest or stomach
  6. burning, crawling, itching, numbness, prickling, “pins and needles”, or tingling feeling
  7. constipation
  8. continuing ringing or buzzing or other unexplained noise in the ears
  9. cracked, dry, or scaly skin
  10. crying
  11. decrease in frequency of urination
  12. degenerative disease of the joint
  13. depersonalization
  14. diarrhea
  15. difficulty with moving
  16. difficulty with passing urine (dribbling)
  17. dysphoria
  18. ear pain
  19. enlarged abdomen or stomach
  20. euphoria
  21. excess air or gas in the stomach or intestines
  22. excessive muscle tone, muscle tension or tightness
  23. fear
  24. feeling sad or empty
  25. hearing loss
  26. heartburn
  27. inability to have or keep an erection
  28. increase in heart rate
  29. increased hair growth, especially on the face
  30. increased urge to urinate during the night
  31. indigestion
  32. irritation in the mouth
  33. joint pain or swelling
  34. leg cramps
  35. loss of bladder control
  36. loss of energy or weakness
  37. loss of interest or pleasure
  38. loss of strength
  39. lower abdominal or stomach pain
  40. muscle aches, pain, stiffness, or weakness
  41. nervousness
  42. pain in the back, ribs, arms, or legs
  43. pain or burning in the throat
  44. pain or tenderness around the eyes and cheekbones
  45. paranoia
  46. pelvic pain
  47. quick to react or overreact emotionally
  48. rapid breathing
  49. rapidly changing moods
  50. inflammation, redness, or swelling of the gums or mouth
  51. shaking or trembling
  52. shivering
  53. sleepiness
  54. sunken eyes
  55. swelling
  56. swelling of the scrotum
  57. tender or enlarged gums
  58. tenderness in the stomach area
  59. thickening of the skin
  60. trouble concentrating
  61. trouble sleeping
  62. waking to urinate at night

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.